Current Cardiology Reports

, Volume 12, Issue 5, pp 429–439

Antegrade, Retrograde, and Combination Strategies for Chronic Total Occlusions

Authors

  • Philippe Genereux
    • Columbia University Medical Center
    • Columbia University Medical Center
Article

DOI: 10.1007/s11886-010-0131-8

Cite this article as:
Genereux, P. & Dangas, G. Curr Cardiol Rep (2010) 12: 429. doi:10.1007/s11886-010-0131-8

Abstract

Chronic total occlusion (CTO) represents one of the most challenging lesion subsets faced by the interventional cardiologist. CTO is a common problem, being present in more than 30% of patients undergoing coronary angiography. Over the past 10 years, the success rate of recanalization has increased from approximately 50–85%. Developments in guidewire technology, imaging technique, and coronary devices have contributed to the improved prognosis of patients affected by a CTO lesion. Enhancement in antegrade and retrograde techniques of recanalization also result in improved outcomes. Benefits of CTO recanalization may include symptom relief, decreased need for coronary artery bypass graft surgery, improved left ventricular ejection fraction, and in some cases an improved survival.

Keywords

Chronic total occlusionAngioplastyCoronary artery disease

Clinical Trial Acronyms

COURAGE

Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation

OAT

Occluded Artery Trial

TOAST-GISE

Total Occlusion Angioplasty Study

Copyright information

© Springer Science+Business Media, LLC 2010