Current Cardiology Reports

, Volume 12, Issue 1, pp 14–19

Primary Intracranial Stenting in Acute Ischemic Stroke

  • Gregory J. Velat
  • Brian L. Hoh
  • Elad I. Levy
  • J Mocco
Article

DOI: 10.1007/s11886-009-0069-x

Cite this article as:
Velat, G.J., Hoh, B.L., Levy, E.I. et al. Curr Cardiol Rep (2010) 12: 14. doi:10.1007/s11886-009-0069-x

Abstract

Acute intracranial stroke is a major source of morbidity and mortality in the United States. Recent studies have shown improved clinical outcomes for patients who achieve timely arterial recanalization. Multimodal therapies have evolved to meet this end point and include intravenous and/or intra-arterial thrombolysis and mechanical thrombolysis. Modifications to existing balloon-mounted stents commonly used in cardiology have yielded more easily navigable and safer self-expanding intracranial stents that provide rapid arterial recanalization. We review the evolution of acute stroke therapy over the past few decades and the recent results of mechanical thrombolysis, focusing on intracranial stenting in the setting of acute stroke.

Keywords

IschemicStrokeStentingRecanalizationThrombolysis

Clinical Trial Acronyms

ECASS 3

European Cooperative Acute Stroke Study 3

IMS

Interventional Management of Stroke

MERCI

Mechanical Embolus Removal in Cerebral Ischemia

NIHSS

National Institutes of Health Stroke Scale

NINDS

National Institute of Neurological Disorders and Stroke

PROACT

Prolyse in Acute Cerebral Thromboembolism

SARIS

Stent-Assisted Recanalization in Acute Ischemic Stroke

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Gregory J. Velat
    • 1
  • Brian L. Hoh
    • 1
  • Elad I. Levy
    • 2
    • 3
  • J Mocco
    • 1
  1. 1.Department of Neurological Surgery, McKnight Brain InstituteUniversity of FloridaGainesvilleUSA
  2. 2.Departments of Neurosurgery and Radiology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New YorkBuffaloUSA
  3. 3.Department of Neurosurgery, Millard Fillmore Gates Hospital, Kaleida HealthBuffaloUSA