Current Cardiology Reports

, Volume 4, Issue 4, pp 334–340

Early invasive strategies for acute coronary syndromes

  • Martin J. Quinn
  • Sorin J. Brener

DOI: 10.1007/s11886-002-0070-0

Cite this article as:
Quinn, M.J. & Brener, S.J. Curr Cardiol Rep (2002) 4: 334. doi:10.1007/s11886-002-0070-0


Early coronary angiography and percutaneous or operative revascularization is now the treatment of choice for both ST- and non-ST-segment elevation acute coronary syndromes (ACS). In non-ST-segment elevation ACS this strategy produces a 18% to 22% reduction in ischemic outcomes at 6 months and prevents 1.7 deaths, 2.0 nonfatal infarcts and 20 readmissions per 100 treated patients at 1-year follow-up. Early angiography allows definition of coronary anatomy and assessment of left ventricular function, both important predictors of long-term risk. Intracoronary stenting and intravenous glycoprotein IIb/IIIa antagonists have improved outcome in percutaneous revascularization and should be used in the majority of ACS patients undergoing PCI. Initial costs are higher with an early invasive strategy; however, these are offset by reductions in rehospitalizations and later ischemic complications.

Copyright information

© Current Science Inc 2002

Authors and Affiliations

  • Martin J. Quinn
    • 1
  • Sorin J. Brener
    • 1
  1. 1.Department of Cardiovascular MedicineThe Cleveland Clinic FoundationClevelandUSA

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