, Volume 3, Issue 1, pp 5-12
Date: 29 Mar 2008

Neurogenic bladder from multiple sclerosis

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Multiple sclerosis (MS) is an autoimmune disorder affecting the central nervous system. Because MS is a chronic disease that can affect any part of the central nervous system, most patients experience voiding dysfunction during the course of the disease. Depending on the site of plaques within the central nervous system, various complaints may arise. Familiarity is required with the evaluation of patients with MS and the available treatment armamentarium. Preservation of the upper urinary tracts is of primary importance. Newer technologies, such as sacral neuromodulation and chemodenervation with botulinum toxin A, can achieve control of urologic symptoms without extensive surgery. This review focuses on the diagnosis, evaluation, and treatment of patients with MS.