Current Atherosclerosis Reports

, Volume 12, Issue 4, pp 217-224

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Recent Advances in Childhood Arterial Ischemic Stroke

  • Christine K. FoxAffiliated withUniversity of California, San Francisco Email author 
  • , Heather J. FullertonAffiliated withUniversity of California, San Francisco


Although many underlying diseases have been reported in the setting of childhood arterial ischemic stroke, emerging research demonstrates that non-atherosclerotic intracerebral arteriopathies in otherwise healthy children are prevalent. Minor infections may play a role in arteriopathies that have no other apparent underlying cause. Although stroke in childhood differs in many aspects from adult stroke, few systematic studies specific to pediatrics are available to inform stroke management. Treatment trials of pediatric stroke are required to determine the best strategies for acute treatment and secondary stroke prevention. The high cost of pediatric stroke to children, families, and society demands further study of its risk factors, management, and outcomes. This review focuses on the recent findings in childhood arterial ischemic stroke.


Childhood stroke Arterial ischemic stroke Cerebral arteriopathy Thrombolysis Stroke outcomes