Evidence-based management of dyslipidemias in women
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- LaRosa, J.C. Curr Atheroscler Rep (2003) 5: 379. doi:10.1007/s11883-003-0009-y
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Women and men are both susceptible to coronary artery disease (CAD). The predictors or risk factors of CAD are qualitatively identical, although low-density lipoprotein is less of a predictor, and high-density lipoprotein and triglycerides are more predictive in women. Diabetes is also a stronger predictor of CAD in women. Lowering of low-density lipoprotein cholesterol is as important in women as in men, as demonstrated in clinical trials. Hormone replacement therapy has not been proven in trials to prevent CAD and may even promote it in some patients. The role of emerging risk factors in CAD prevention is still unclear in either gender. Trials now in progress should clarify this issue.