Current Allergy and Asthma Reports

, Volume 10, Issue 5, pp 340–348

Component Resolved Testing for Allergic Sensitization

Article

DOI: 10.1007/s11882-010-0133-z

Cite this article as:
Skamstrup Hansen, K. & Poulsen, L.K. Curr Allergy Asthma Rep (2010) 10: 340. doi:10.1007/s11882-010-0133-z

Abstract

Component resolved diagnostics introduces new possibilities regarding diagnosis of allergic diseases and individualized, allergen-specific treatment. Furthermore, refinement of IgE-based testing may help elucidate the correlation or lack of correlation between allergenic sensitization and allergic disease. Novel tools to predict severe outcomes and to plan for allergen-specific treatment are necessary, and because only a small amount of blood is needed to test for a multitude of allergens and allergenic components, component resolved diagnostics is promising. A drawback is the risk of overdiagnosis and misinterpretation of the complex results of such tests. Also, the practical use and selection of allergenic components need to be evaluated in large studies including well-characterized patients and healthy, sensitized controls and with representation of different geographical regions.

Keywords

Allergen Allergenic component Cross-reactivity CRD Diagnostics Individualized treatment Pollen-related food allergy Sensitization pattern 

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Pediatrics, The Juliane Marie CentreCopenhagen University Hospital, GentofteHellerupDenmark
  2. 2.Allergy ClinicCopenhagen University HospitalGentofteDenmark

Personalised recommendations