, Volume 7, Issue 6, pp 459-463
Date: 18 Mar 2008

Exhaled nitric oxide: A test for diagnosis and control of asthma?

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Abstract

The fractional concentration of nitric oxide (FENO) in exhaled breath is a noninvasive marker of airway inflammation in asthma. The precise role of FENO in the asthma management algorithm has not been defined. However, there are compelling data for use of FENO for diagnosing asthma, assessing control and severity, titrating inhaled corticosteroids, and detecting ongoing airway inflammation. This article reviews the biology of nitric oxide in airway pathology and its role in asthma.