The World Health Organization (WHO) Histologic Classification of Thymomas: A Reanalysis
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- Moran, C.A. & Suster, S. Curr. Treat. Options in Oncol. (2008) 9: 288. doi:10.1007/s11864-009-0084-6
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The histologic classification of thymomas has remained for many years an area of conflict. In recent years, the World Health Organization (WHO) presented a proposal for the classification of these tumors, which has been widely adopted in many countries throughout the world. Two successive versions of this classification have been presented in recent years; however, controversy still exists regarding its accuracy and usefulness in clinical practice. We present a review of the current WHO classification of thymomas, with a discussion of some of the inconsistencies and limitations and the possible alternatives to the current approach for the histopathologic classification of these tumors.