Current Treatment Options in Oncology

, Volume 2, Issue 1, pp 7–13

Locally advanced head and neck cancer

  • Merrill S. Kies
  • Charles L. Bennett
  • Everett E. Vokes

DOI: 10.1007/s11864-001-0012-x

Cite this article as:
Kies, M.S., Bennett, C.L. & Vokes, E.E. Curr. Treat. Options in Oncol. (2001) 2: 7. doi:10.1007/s11864-001-0012-x

Opinion statement

The simultaneous administration of chemotherapy and radiation has produced a significant impact on the treatment of advanced squamous cell carcinomas of the head and neck. Although no single regimen has emerged as the “standard” approach, recent trials have consistently demonstrated the superiority of combined treatment programs over radiotherapy alone for local tumor control and overall survival. More-over, multimodal treatment has emerged with important ancillary goals of organ preservation, improved cosmesis, and enhancement of quality of life. With improving survival in all stages of disease, much attention can be given to identifying effective measures to reduce the risk of metachronous primary cancers in this high-risk group.

Copyright information

© Current Science Inc 2001

Authors and Affiliations

  • Merrill S. Kies
    • 1
  • Charles L. Bennett
    • 2
  • Everett E. Vokes
    • 3
  1. 1.Thoracic/Head and Neck Medical OncologyUniversity of Texas M. D. Anderson Cancer CenterHoustonUSA
  2. 2.Chicago VA Healthcare System/Lakeside DivisionChicagoUSA
  3. 3.University of ChicagoChicagoUSA