Irish Journal of Medical Science

, Volume 180, Issue 1, pp 7–13

Vitamin D insufficiency: a common and treatable problem in the Irish population

Review Article

DOI: 10.1007/s11845-010-0512-4

Cite this article as:
O’Malley, G. & Mulkerrin, E. Ir J Med Sci (2011) 180: 7. doi:10.1007/s11845-010-0512-4



Vitamin D insufficiency is an extremely common condition particularly in the older Irish population. This is a consequence of Ireland’s geographical position and climate. A recent study showed more than 75% of a cohort of older Irish females had vitamin D insufficiency.


We outline the definition of vitamin D insufficiency and deficiency, its sources and metabolism as well as the clinical consequences of deficiency. We explore the current guidelines and discuss the pitfalls in the management of vitamin D replacement and in particular address recent Irish data on the feasibility and efficacy of intramuscular treatment.


Vitamin D is important for calcium homeostasis and bone metabolism and reduced levels lead to osteomalacia, exacerbate osteoporosis and increase the risk of falls. Evidence is emerging that vitamin D has a role beyond musculoskeletal health and may impact on the cardiovascular and autoimmune systems, as well as the risk of malignancy.


Vitamin DInsufficiencyOsteoporosisFallsIreland

Copyright information

© Royal Academy of Medicine in Ireland 2010

Authors and Affiliations

  1. 1.Department of Medicine for the ElderlyUniversity HospitalGalwayIreland