Irish Journal of Medical Science

, Volume 179, Issue 3, pp 431–433

Recombinant activated factor VII to control life-threatening haemorrhagic radiation cystitis

  • S. S. Connolly
  • F. T. D’Arcy
  • M. O. Corcoran
Brief Report

DOI: 10.1007/s11845-009-0324-6

Cite this article as:
Connolly, S.S., D’Arcy, F.T. & Corcoran, M.O. Ir J Med Sci (2010) 179: 431. doi:10.1007/s11845-009-0324-6



The use of recombinant activated factor VII has been described for many clinical scenarios, but the value of this therapeutic agent for life-threatening haemorrhagic cystitis remains novel.


We describe a case of persistent life-threatening haemorrhagic radiation cystitis, and discuss current knowledge of this therapy including potential complications.


Control of haemorrhage was successfully achieved only after use of this agent.


This therapy deserves mention in any future management algorithm devised for this condition.


Recombinant activated factor 7Haemorrhagic radiation cystitis

Copyright information

© Royal Academy of Medicine in Ireland 2009

Authors and Affiliations

  • S. S. Connolly
    • 1
  • F. T. D’Arcy
    • 1
  • M. O. Corcoran
    • 1
  1. 1.Department of UrologyUniversity College Hospital GalwayGalwayIreland