, Volume 180, Issue 4, pp 889-891
Date: 31 Jan 2009

Metastatic uterine leiomyosarcoma presenting as a breast lump

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Abstract

Background

It is uncommon to encounter a breast metastasis from an extramammary malignancy and even rarer from a uterine leiomyosarcoma.

Aims

We describe the third case report in the medical literature of a breast metastasis from a uterine leiomyosarcoma.

Methods

We report the management of a 56-year-old patient who presented with a breast lump 3 years after hysterectomy for a fibroid uterus. We conducted a literature review of breast leiomyosarcomas.

Results

The excision of the breast mass revealed a low-grade leiomyosarcoma. Radiographic examinations demonstrated metastases to the lung, liver, pelvis and bone. Retrospective pathology review of her uterus identified a small focus of leiomyosarcoma. She received chemotherapy and palliative radiotherapy but passed away within few months.

Conclusion

Metastasis to the breast from a non-breast primary is generally a sign of disseminated disease and; thus, a poor prognostic indicator.