Original Article

Irish Journal of Medical Science

, Volume 177, Issue 1, pp 11-17

Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU

  • J. JanotaAffiliated withDepartment of Paediatrics, The Rotunda Hospital Email author 
  • , J. SimakAffiliated withCenter for Biologics Evaluation and Research, Food and Drug Administration
  • , Z. StranakAffiliated withInstitute for Care of Mother and Child
  • , T. MatthewsAffiliated withDepartment of Paediatrics, The Rotunda HospitalThe Children’s Hospital
  • , T. ClarkeAffiliated withDepartment of Paediatrics, The Rotunda HospitalThe Children’s Hospital
  • , D. CorcoranAffiliated withDepartment of Paediatrics, The Rotunda HospitalThe Children’s Hospital

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Abstract

Background

The neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality.

Aim

To test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants.

Methods

The system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid–base balance in 24-h intervals during the first 28 days of life.

Results

A NEOMOD of ≥9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality.

Conclusions

The NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality.

Keywords

Mortality Multiple organ dysfunction Preterm newborn Scoring system