Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU
- J. JanotaAffiliated withDepartment of Paediatrics, The Rotunda Hospital Email author
- , J. SimakAffiliated withCenter for Biologics Evaluation and Research, Food and Drug Administration
- , Z. StranakAffiliated withInstitute for Care of Mother and Child
- , T. MatthewsAffiliated withDepartment of Paediatrics, The Rotunda HospitalThe Children’s Hospital
- , T. ClarkeAffiliated withDepartment of Paediatrics, The Rotunda HospitalThe Children’s Hospital
- , D. CorcoranAffiliated withDepartment of Paediatrics, The Rotunda HospitalThe Children’s Hospital
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The neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality.
To test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants.
The system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid–base balance in 24-h intervals during the first 28 days of life.
A NEOMOD of ≥9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality.
The NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality.
KeywordsMortality Multiple organ dysfunction Preterm newborn Scoring system
- Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU
Irish Journal of Medical Science
Volume 177, Issue 1 , pp 11-17
- Cover Date
- Print ISSN
- Online ISSN
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- Multiple organ dysfunction
- Preterm newborn
- Scoring system
- Industry Sectors
- Author Affiliations
- 1. Department of Paediatrics, The Rotunda Hospital, Parnell Square, Dublin 1, Ireland
- 2. Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA
- 3. Institute for Care of Mother and Child, Praha, Czech Republic
- 4. The Children’s Hospital, Temple Street, Dublin, Ireland