Overview Surface Modification in Bioapplications

JOM

, Volume 58, Issue 7, pp 52-56

The use of functionally gradient materials in medicine

  • Roger J. NarayanAffiliated withJoint Department of Biomedical Engineering, University of North Carolina and North Carolina State University
  • , Linn W. HobbsAffiliated withDepartment of Materials Science and Engineering at Massachusetts Institute of Technology in Cambridge
  • , Chunming JinAffiliated withJoint Department of Biomedical Engineering, University of North Carolina and North Carolina State University
  • , Afsaneh RabieiAffiliated withDepartment of Mechanical and Aerospace Engineering at North Carolina State University in Raleigh

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Abstract

Functionally gradient materials are characterized by uniform changes in composition, crystallinity, and/or grain structure, which may provide unique biological, chemical, or mechanical functionalities in next-generation medical devices. In this article, the development of functionally gradient Zr−Nb alloys, hydroxyapatite coatings, and diamondlike carbon-metal coatings for medical applications is reviewed.