Intermittent active motion versus immobilization in the treatment of Staphylococcus aureus -induced arthritis in a rabbit model
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This study has evaluated the effects of immobilization versus intermittent active motion on cartilage and on antibiotic efficacy in a rabbit septic arthritis model.
Rabbits were infected and assigned to one of four groups: group 1, no treatment without immobilization (allowing intermittent active motion); group 2, cast; group 3, oxacillin without immobilization; group 4, oxacillin and cast. Animals were sacrificed 21 days later. Bacterial counts and lateral radiograms were performed. A radiological score was calculated.
Immobilization had no effect on oxacillin efficacy and a deleterious effect on the radiological score.
Intermittent active motion has allowed a better cartilage healing during the treatment of septic arthritis.
- Intermittent active motion versus immobilization in the treatment of Staphylococcus aureus-induced arthritis in a rabbit model
Journal of Children's Orthopaedics
Volume 2, Issue 6 , pp 491-495
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- Intermittent active motion
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- 1. Laboratoire d’Antibiologie Clinique et Expérimentale UPRES EA 3826, Faculté de Médecine, Université de Nantes, Nantes, France
- 2. Service de Chirurgie Pédiatrique, Hôpital Mère Enfant, Centre Hospitalier Universitaire de Nantes, Quai Moncousu, 44093, Nantes Cedex, France