Article

Mathematics in Computer Science

, Volume 1, Issue 4, pp 655-672

First online:

A Tutorial on Computational Cluster Analysis with Applications to Pattern Discovery in Microarray Data

  • Raffaele GiancarloAffiliated withDipartimento di Matematica ed Applicazioni, Universitá di Palermo Email author 
  • , Davide ScaturroAffiliated withDipartimento di Matematica ed Applicazioni, Universitá di Palermo
  • , Filippo UtroAffiliated withDipartimento di Matematica ed Applicazioni, Universitá di Palermo

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Abstract.

Microarrays offer unprecedented possibilities for the so-called omic, e.g., genomic and proteomic, research. However, they are also quite challenging data to analyze. The aim of this paper is to provide a short tutorial on the most common approaches used for pattern discovery and cluster analysis as they are currently used for microarrays, in the hope to bring the attention of the Algorithmic Community on novel aspects of classification and data analysis that deserve attention and have potential for high reward.

Mathematics Subject Classification (2000).

Primary 68Q25, 68Q05

Keywords.

Clustering algorithms hypothesis testing in statistics microarrays data analysis