Racial/ethnic differences in quality of life after diagnosis of breast cancer
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Most studies on quality of life of breast cancer survivors have not had adequate representation of ethnic minorities. The purpose of this study was to determine whether racial/ethnic differences in quality of life exist between white, African American, and Latina women in the early stages of survivorship.
2268 women were identified by two Surveillance, Epidemiology and End Results (SEER) registries (6/05–2/07) and asked to complete a survey (mean 9 months post-diagnosis, 72.1% response rate). Latina and African American women were over-sampled. Regression models compared quality of life across race/ethnicity (white, African American, Latina [low vs. high acculturation]), sequentially controlling for sociodemographics, clinical, and treatment factors.
There were significant racial/ethnic differences in quality of life controlling for sociodemographics, clinical factors and treatment factors. Lower acculturated Latinas compared to whites had significantly lower functional well-being, emotional well-being, and breast cancer concerns (p values < 0.05). African Americans had significantly higher emotional well-being than whites. Age, co-morbidities, cancer stage, and chemotherapy also influenced quality of life. A significant interaction was found between race/ethnicity and age for physical well-being (p = 0.041) and for emotional well-being (p = 0.042). Specifically, racial/ethnic differences were only observed among older women (≥50 years), with less acculturated Latinas reporting the lowest quality of life.
Racial/ethnic differences in quality of life exist during the cancer survivorship period. Latinas with low acculturation are a particularly vulnerable subgroup.
Greater attention should be devoted to identifying women disproportionately affected by breast cancer and developing interventions targeting their unique survivorship concerns.
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- Racial/ethnic differences in quality of life after diagnosis of breast cancer
Journal of Cancer Survivorship
Volume 3, Issue 4 , pp 212-222
- Cover Date
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- Springer US
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- Breast cancer
- Quality of life
- Minority health
- Racial/ethnic differences
- Industry Sectors
- Author Affiliations
- 1. Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, MI, USA
- 2. Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA, USA
- 3. Veterans Administration Center for Practice Management, Ann Arbor Veterans Administration Health Care System and Outcomes Research, University of Michigan Medical Center, Ann Arbor, MI, USA
- 4. Division of General Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
- 5. Department of Medicine, Division of Hematology and Oncology, University of Michigan, Ann Arbor, MI, USA
- 6. Department of Surgery, University of Michigan, Ann Arbor, MI, USA
- 7. Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
- 8. Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA
- 9. Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor, MI, USA