Internal and Emergency Medicine

, Volume 8, Supplement 1, pp 55–56

Metabolic and cardiovascular effects of beta cell replacement in type 1 diabetes

  • Piero Marchetti
  • Margherita Occhipinti
  • Lorenzo Rondinini
  • Rita Mariotti
  • Gabriella Amorese
  • Massimiliano Barsotti
  • Fabio Vistoli
  • Ugo Boggi
Review

DOI: 10.1007/s11739-013-0912-3

Cite this article as:
Marchetti, P., Occhipinti, M., Rondinini, L. et al. Intern Emerg Med (2013) 8(Suppl 1): 55. doi:10.1007/s11739-013-0912-3
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Abstract

Type 1 diabetes is associated with high morbidity and mortality, mostly due to the acute and chronic complications of the disease. Restoration of the lost beta cell mass by pancreas transplantation is the treatment of choice in selected type 1 diabetic patients. Growing data show that successful pancreas transplantation normalizes the metabolic alterations of diabetes, and can slow the progression, stabilize, and even favor the regression of secondary complications of the disease, including those at the cardiovascular level.

Keywords

Type 1 diabetes Beta cell Pancreas transplantation 

Copyright information

© SIMI 2013

Authors and Affiliations

  • Piero Marchetti
    • 1
  • Margherita Occhipinti
    • 1
  • Lorenzo Rondinini
    • 1
  • Rita Mariotti
    • 1
  • Gabriella Amorese
    • 1
  • Massimiliano Barsotti
    • 1
  • Fabio Vistoli
    • 1
  • Ugo Boggi
    • 1
  1. 1.Department of Clinical and Experimental MedicineUniversity of Pisa, Cisanello AOUP University HospitalPisaItaly

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