, Volume 7, Issue 2 Supplement, pp 127-129
Date: 01 Aug 2012

Renal angiomyolipomatosis and Kaposi’s sarcoma: a possible link disrupted by sirolimus

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access
This is an excerpt from the content

Dear Editor,

We describe a case of woman aged 72 years, referred to our division for acute kidney injury (AKI). The patient’s history included renal angiomyolipomatosis that caused a previous left nephrectomy, non-Hodgkin Lymphoma (NHL) and cutaneous Kaposi’s sarcoma (KS).

On August 1996, she presented abdominal pain, and underwent abdomen echo tomography that showed multiple renal hyperechogenic images. Enhanced body CT-scan showed multiple renal lesions compatible with angiomyolipomatosis. One year later, she underwent left nephrectomy, and histological analyses confirmed the diagnosis of renal angiomyolipomatosis.

On August 2008, due to the presence of leukopenia and thrombocytopenia, the patient underwent splenectomy and liver biopsy with diagnosis of NHL. A bone marrow biopsy showed a nodular medullary location of NHL. The patient received chemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP), for a total of six cycles.

At the end of CHOP cycles, she prese ...