Impact of Different Criteria on Type 2 Diabetes Remission Rate After Bariatric Surgery
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
Laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) achieve similar type 2 diabetes mellitus (T2DM) remission rates. Since a great variability exists in defining T2DM remission, an expert panel proposed partial and complete remission criteria that include the maintenance of fasting plasma glucose (FPG) and glycosylated hemoglobin (A1c) objectives for at least 1 year. The 2-year T2DM remission rate and time needed to reach it after LSG or LRYGB were compared using different remission criteria.
This was a prospective cohort study of 55 T2DM subjects operated on with LSG (n = 21) or LRYGB (n = 34). Four models for defining remission were used: Buchwald criteria (FPG <100 mg/dl or A1c <6 %), American Diabetes Association (ADA) complete (FPG <100 mg/dl plus A1c <6 % maintained for at least 1 year), ADA partial (FPG <125 mg/dl with A1c <6.5 % maintained for at least 1 year), and ADA complete without time requirement.
Both groups were comparable, except for higher A1c levels in the LSG group. The remission rate ranged from 43.6 % using ADA complete remission to 92.7 % with Buchwald criteria, with no differences between surgical procedures. Differences were found in the time to achieve remission only when ADA complete remission criteria (5.1 ± 2.9 months LRYGB and 9.0 ± 3.8 months LSG, p = 0.014) and ADA without time requirement criteria (4.9 ± 2.7 months LRYGB and 8.4 ± 3.9 months LSG, p = 0.005) were used.
T2DM remission rate varies widely depending on the criteria used for its definition. Remission occurred sooner after LRYGB when the strictest criteria to define remission were used.
- Impact of Different Criteria on Type 2 Diabetes Remission Rate After Bariatric Surgery
Volume 24, Issue 11 , pp 1881-1887
- Cover Date
- Print ISSN
- Online ISSN
- Springer US
- Additional Links
- Severe obesity
- Laparoscopic sleeve gastrectomy
- Laparoscopic Roux-en-Y gastric bypass
- Type 2 diabetes mellitus remission
- Industry Sectors
- Author Affiliations
- 1. Department of Endocrinology and Nutrition, Hospital del Mar, Passeig Marítim, 25-29, 08003, Barcelona, Spain
- 2. Universitat Autònoma de Barcelona, Barcelona, Spain
- 5. Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Barcelona, Spain
- 3. Unit of Gastrointestinal Surgery, Hospital del Mar, Barcelona, Spain
- 4. CIBEROBN, Madrid, Spain