Obesity Surgery

, Volume 24, Issue 6, pp 971–973

Correlation Between Post Over Preoperative Surrogate Insulin Resistance Indexes’ Ratios and Reversal of Metabolic Syndrome After Roux-en-Y Gastric Bypass

  • Everton Cazzo
  • Francisco Callejas-Neto
  • José Carlos Pareja
  • Elinton Adami Chaim
Brief Communication

DOI: 10.1007/s11695-014-1246-6

Cite this article as:
Cazzo, E., Callejas-Neto, F., Pareja, J.C. et al. OBES SURG (2014) 24: 971. doi:10.1007/s11695-014-1246-6

Abstract

Metabolic syndrome (MetS) is strongly linked to insulin resistance and has a high resolution rate after bariatric surgery. This study aims to determine whether post over preoperative ratios of surrogate insulin resistance markers (HOMA, TyG, and TG/HDL-c) are associated to postsurgical MetS reversal. This is a retrospective cohort study which involved 96 subjects with MetS who underwent Roux-en-Y gastric bypass (RYGB). Post over preoperative ratios of TyG and TG/HDL-c indexes were statistically associated to MetS resolution. The use of these ratios as a way to assess postsurgical insulin sensitivity response appears to be a simple and useful tool in clinical practice.

Keywords

Metabolic syndrome X Insulin resistance Gastric bypass Diabetes mellitus Bariatric surgery 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Everton Cazzo
    • 1
  • Francisco Callejas-Neto
    • 1
  • José Carlos Pareja
    • 1
  • Elinton Adami Chaim
    • 1
  1. 1.Department of Surgery, Faculty of Medical SciencesState University of Campinas (UNICAMP)CampinasBrazil