, Volume 21, Issue 6, pp 794-796

Update: Why Diabetes Does Not Resolve in Some Patients after Bariatric Surgery

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Bariatric surgery provides resolution of co-morbidities of morbid obesity—importantly diabetes type 2. This is initiated by immediate postoperative decrease in intake or assimilation of glucose and is continued by the substantial loss of adipose tissue. Greater weight loss and greater resolution of type 2 diabetes occur after operations that provide rapid passage of nutrients to the hindgut, which likely results in beta-cell stimulation by incretins. Failure of resolution of the diabetes can result from lack of patient compliance, inadequate weight loss, longstanding uncontrolled diabetes, or when the diabetes is actually a type 1.