Obesity Surgery

, Volume 21, Issue 1, pp 125–130

Changes in Ghrelin Levels Following Bariatric Surgery: Review of the Literature

Authors

  • Kevin Tymitz
    • Department of SurgeryGood Samaritan Hospital
  • Amy Engel
    • E. Kenneth Hatton, MD, Institute for Research and EducationGood Samaritan Hospital
  • Sarah McDonough
    • E. Kenneth Hatton, MD, Institute for Research and EducationGood Samaritan Hospital
    • E. Kenneth Hatton, MD, Institute for Research and EducationGood Samaritan Hospital
  • George Kerlakian
    • Department of SurgeryGood Samaritan Hospital
Review

DOI: 10.1007/s11695-010-0311-z

Cite this article as:
Tymitz, K., Engel, A., McDonough, S. et al. OBES SURG (2011) 21: 125. doi:10.1007/s11695-010-0311-z

Abstract

Obesity is a severe health issue that is a global epidemic. Bariatric surgery is an accepted, popular, and effective therapy for weight loss. Ghrelin, a peptide secreted primarily by the fundus cells of the stomach, has been found to impact body weight by its influence on appetite. Although numerous studies have investigated serum ghrelin levels following bariatric surgery, there is no solid agreement yet as to the direction or magnitude of its change, or even its impact on weight loss. Some studies have found an increase in ghrelin, some have found a decrease, and others have found no change in ghrelin following bariatric surgery. The purpose of this review was to establish the impact of ghrelin changes following bariatric surgery.

Keywords

ObesityRoux-en-Y gastric bypassAdjustable gastric bandSleeve gastrectomyBiliopancreatic diversion–pancreatic switchBariatric surgeryWeight lossGhrelinType II diabetes

Copyright information

© Springer Science + Business Media, LLC 2010