Obesity Surgery

, Volume 21, Issue 1, pp 54–60

Prevalence of Endocrine Diseases in Morbidly Obese Patients Scheduled for Bariatric Surgery: Beyond Diabetes

Authors

    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Aldo Pinchera
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Silvia Martinelli
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Giovanna Scartabelli
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Guido Salvetti
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Monica Giannetti
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Andrea Pucci
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Giulia Galli
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Ilaria Ricco
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Giorgia Querci
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Teresa Rago
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Claudio Di Salvo
    • Bariatric Surgery UnitUniversity Hospital of Pisa
  • Marco Anselmino
    • Bariatric Surgery UnitUniversity Hospital of Pisa
  • Paolo Vitti
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
  • Ferruccio Santini
    • Department of Endocrinology and KidneyUniversity Hospital of Pisa
Clinical Research

DOI: 10.1007/s11695-010-0297-6

Cite this article as:
Fierabracci, P., Pinchera, A., Martinelli, S. et al. OBES SURG (2011) 21: 54. doi:10.1007/s11695-010-0297-6

Abstract

Background

Bariatric surgery allows stable body weight reduction in morbidly obese patients. In presurgical evaluation, obesity-related co-morbidities must be considered, and a multidisciplinary approach is recommended. Precise guidelines concerning the endocrinological evaluation to be performed before surgery are not available. The aim of this study was to evaluate the prevalence of common endocrine diseases in a series of obese patients scheduled for bariatric surgery.

Methods

We examined 783 consecutive obese subjects (174 males and 609 females) aged 18–65 years, who turned to the obesity centre of our department from January 2004 to December 2007 for evaluation before bariatric surgery. Thyroid, parathyroid, adrenal and pituitary function was evaluated by measurement of serum hormones. Specific imaging or supplementary diagnostic tests were performed when indicated.

Results

The overall prevalence of endocrine diseases, not including type 2 diabetes mellitus, was 47.4%. The prevalence of primary hypothyroidism was 18.1%; pituitary disease was observed in 1.9%, Cushing syndrome in 0.8%, while other diseases were found in less than 1% of subjects. Remarkably, the prevalence of newly diagnosed endocrine disorders was 16.3%.

Conclusions

A careful endocrinological evaluation of obese subjects scheduled for bariatric surgery may reveal undiagnosed dysfunctions that require specific therapy and/or contraindicate the surgical treatment in a substantial proportion of patients. These results may help to define the extent of the endocrinological screening to be performed in obese patients undergoing bariatric surgery.

Keywords

Bariatric surgeryObese patientsEndocrinological evaluation

Copyright information

© Springer Science + Business Media, LLC 2010