Obesity Surgery

, Volume 20, Issue 10, pp 1448–1455

Morbid Obesity and Sleeve Gastrectomy: How Does It Work?

  • Joanna Papailiou
  • Konstantinos Albanopoulos
  • Konstantinos G. Toutouzas
  • Christos Tsigris
  • Nikolaos Nikiteas
  • George Zografos
Review

DOI: 10.1007/s11695-010-0148-5

Cite this article as:
Papailiou, J., Albanopoulos, K., Toutouzas, K.G. et al. OBES SURG (2010) 20: 1448. doi:10.1007/s11695-010-0148-5

Abstract

Laparoscopic sleeve gastrectomy is known to be a safe and effective procedure for treating morbid obesity and is performed with increasing frequency both in Europe and the USA. Despite its broad use, many questions about the remaining gastric tube diameter, its long-term efficacy, its effects on gastric emptying, and the hormones involved still remain to be answered. In order to use such a relatively new surgical procedure wisely, it is essential for every surgeon and physician to understand how sleeve gastrectomy acts in obesity and what its potential benefits on the patients’ metabolism are. This review focuses on the most important pathophysiologic questions referred to sleeve gastrectomy on the literature so far, in an attempt to evaluate the different issues still pending on the subject.

Keywords

ObesityBariatric surgeryMetabolic surgerySleeve gastrectomyGhrelinGLP-1Gastric emptying

Copyright information

© Springer Science + Business Media, LLC 2010

Authors and Affiliations

  • Joanna Papailiou
    • 1
  • Konstantinos Albanopoulos
    • 1
  • Konstantinos G. Toutouzas
    • 1
  • Christos Tsigris
    • 2
  • Nikolaos Nikiteas
    • 3
  • George Zografos
    • 1
  1. 1.1st Department of Propaedeutic Surgery, Hippocration HospitalAthens Medical SchoolAthensGreece
  2. 2.1st Department of Surgery, Laikon HospitalAthens Medical SchoolGoudi, AthensGreece
  3. 3.2nd Department of Surgery, Laikon HospitalAthens Medical SchoolGoudi, AthensGreece