Obesity Surgery

, Volume 21, Issue 8, pp 1194–1202

Short-Term Carbohydrate-Restricted Diet for Weight Loss in Severely Obese Women

  • Andresa de Toledo Triffoni-Melo
  • Ingrid Dick-de-Paula
  • Guilherme Vannucchi Portari
  • Alceu Afonso Jordao
  • Paula Garcia Chiarello
  • Rosa Wanda Diez-Garcia
Clinical Research

DOI: 10.1007/s11695-010-0110-6

Cite this article as:
de Toledo Triffoni-Melo, A., Dick-de-Paula, I., Portari, G.V. et al. OBES SURG (2011) 21: 1194. doi:10.1007/s11695-010-0110-6

Abstract

Background

Weight loss in bariatric pre-surgery period reduces surgical complications, surgery time, blood loss, and length of hospital stay. Carbohydrate-restricted diets have been used as an alternative for weight loss. We tested the efficacy of a low-calorie carbohydrate-restricted diet (RD) for short-term weight loss in women with severe obesity and evaluate its metabolic effects in relation to a conventional low-calorie diet (CD).

Methods

The subjects received a 1,200-kcal diet with or without carbohydrate restriction for a period of 1 week in the hospital. Nineteen obesity class III women were distributed into two groups: experimental (n = 10) and control (n = 9). The following variables were assessed at the beginning and end of the study: anthropometric measurements, body composition, resting energy expenditure, substrate oxidation, and biochemical tests.

Results

Compared with CD, RD led to larger weight loss (2.6 and 4.4 kg, respectively; p = 0.01) and waist circumference reduction (p < 0.01). Among the assessed biochemical indicators, only plasma and urine acetone levels were different (p < 0.01); higher values were found in the experimental group with no symptoms and other diet-related complaints. There was also a significant decrease in triglycerides and carbohydrate oxidation, as well as a significant enhancement in lipid oxidation in the RD group.

Conclusion

Short-term RD was more efficient than CD regarding quick weight loss and waist circumference reduction, which may favor gastroplasty. Also, RD did not lead adverse metabolic effects.

Keywords

Low-carbohydrate dietWeight lossKetosisMorbid obesity

Abbreviations

RD

low-calorie carbohydrate-restricted diet

CD

conventional low-calorie diet

HCFMRP-USP

Clinical Hospital, School of Medicine of Ribeirão Preto, University of São Paulo

BMI

body mass index

AC

arm circumference

WC

waist circumference in the navel

WC1

waist circumference 10 cm above the WC

WC2

waist circumference 20 cm above the WC

HOMA-IR

homeostasis model assessment-insulin resistance

SD

standard deviation

REE

resting energy expenditure

FM

fat mass

LM

lean mass

RQ

respiratory quotient

TEV

total energy value

Copyright information

© Springer Science + Business Media, LLC 2010

Authors and Affiliations

  • Andresa de Toledo Triffoni-Melo
    • 1
  • Ingrid Dick-de-Paula
    • 2
  • Guilherme Vannucchi Portari
    • 3
  • Alceu Afonso Jordao
    • 4
  • Paula Garcia Chiarello
    • 4
  • Rosa Wanda Diez-Garcia
    • 4
  1. 1.Department of Internal Medicine, School of Medicine of Ribeirão PretoUniversity of São PauloRibeirão PretoBrazil
  2. 2.Clinical Hospital, School of Medicine of Ribeirão PretoUniversity of São PauloRibeirão PretoBrazil
  3. 3.Faculty of NutritionFederal University of Triangulo MineiroUberabaBrazil
  4. 4.Nutrition and Metabolism, Department of Internal Medicine, School of Medicine of Ribeirão PretoUniversity of São PauloRibeirão PretoBrazil