Obesity Surgery

, 18:1611

Evidence-based Review of the Bioenterics Intragastric Balloon for Weight Loss

Review

DOI: 10.1007/s11695-008-9593-9

Cite this article as:
Dumonceau, JM. OBES SURG (2008) 18: 1611. doi:10.1007/s11695-008-9593-9

Abstract

We reviewed clinical studies performed with the Bioenterics intragastric balloon (BIB) to promote weight loss. Thirty studies were included [18 prospective (5 randomized), 12 retrospective], totaling 4,877 patients. Only one of three sham-controlled trials found a significantly higher weight loss with the BIB vs the sham procedure plus exhaustive follow-up. In nonrandomized studies, weight loss with the BIB averaged 17.8 kg (range, 4.9–28.5), corresponding to BMI changes of 4.0–9.0 kg/m2. Comorbidities resolved or improved in 52–100% of patients. Best short-term results were observed in patients devoid of binge eating disorder with a BMI in the 30.0–40.0 kg/m2 range; the BIB also helped to prepare superobese patients for bariatric surgery. Severe complications were exceptional (gastric perforation and intestinal obstruction; 0.2% each); digestive intolerance prompted early BIB removal in 2.5% of patients. Long-term (≥2 years) results are awaited, as well as well-designed studies to define the best indications for this therapy.

Keywords

ObesityGastrointestinal endoscopyGastric balloonWeight loss

Abbreviations

BMI

body mass index

BIB

Bioenterics intragastric balloon

Copyright information

© Springer Science + Business Media, LLC 2008

Authors and Affiliations

  1. 1.Division of Gastroenterology and HepatologyGeneva University HospitalsGenevaSwitzerland