, Volume 18, Issue 12, pp 1611-1617

Evidence-based Review of the Bioenterics Intragastric Balloon for Weight Loss

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

We reviewed clinical studies performed with the Bioenterics intragastric balloon (BIB) to promote weight loss. Thirty studies were included [18 prospective (5 randomized), 12 retrospective], totaling 4,877 patients. Only one of three sham-controlled trials found a significantly higher weight loss with the BIB vs the sham procedure plus exhaustive follow-up. In nonrandomized studies, weight loss with the BIB averaged 17.8 kg (range, 4.9–28.5), corresponding to BMI changes of 4.0–9.0 kg/m2. Comorbidities resolved or improved in 52–100% of patients. Best short-term results were observed in patients devoid of binge eating disorder with a BMI in the 30.0–40.0 kg/m2 range; the BIB also helped to prepare superobese patients for bariatric surgery. Severe complications were exceptional (gastric perforation and intestinal obstruction; 0.2% each); digestive intolerance prompted early BIB removal in 2.5% of patients. Long-term (≥2 years) results are awaited, as well as well-designed studies to define the best indications for this therapy.

Conflict of interest: none