Obesity Surgery

, Volume 17, Issue 10, pp 1399–1407

Implications of Altered Gastrointestinal Motility in Obesity

  • T. K. Gallagher
  • J. G. Geoghegan
  • A. W. Baird
  • D. C. Winter
Review

DOI: 10.1007/s11695-007-9221-0

Cite this article as:
Gallagher, T.K., Geoghegan, J.G., Baird, A.W. et al. OBES SURG (2007) 17: 1399. doi:10.1007/s11695-007-9221-0

The onset of obesity occurs as a result of an imbalance between nutrient consumption/absorption and energy expenditure. Gastrointestinal (GI) motility plays a critical role in the rate of consumption of foods, digestion, and absorption of nutrients. Various segments of the GI tract coordinate in a complex yet precise way, to control the process of food consumption, digestion, and absorption of nutrients. GI motility not only regulates the rates at which nutrients are processed and absorbed in the gut, but also, via mechanical and neurohormonal methods, participates in the control of appetite and satiety. Altered GI motility has frequently been observed in obese patients, the significance of which is incompletely understood. However, these alterations can be considered as potential contributing factors in the development and maintenance of obesity and changed eating behavior. Therapies aimed at regulating or counteracting the observed changes in GI motility are being actively explored and applied clinically in the management of obese patients.

Key words

Electrical stimulation motility obesity pacing reflux 

Copyright information

© Springer Science + Business Media B.V. 2007

Authors and Affiliations

  • T. K. Gallagher
    • 1
    • 3
    • 4
    • 5
  • J. G. Geoghegan
    • 2
    • 4
  • A. W. Baird
    • 3
  • D. C. Winter
    • 1
    • 4
  1. 1.Institute of Clinical Outcomes in Research and Education (ICORE)Palo AltoUSA
  2. 2.Dept. of SurgerySt. Columcille’s HospitalLoughlinstownRepublic of Ireland
  3. 3.Dept of Veterinary PhysiologyUCD College of Life Sciences Graduate SchoolDublinRepublic of Ireland
  4. 4.Dept. of SurgerySt Vincent’s University HospitalElm ParkRepublic of Ireland
  5. 5.ClontarfRepublic of Ireland

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