Obesity Surgery

, Volume 17, Issue 4, pp 550–552

Laparoscopic Spleen-Preserving Distal Pancreatectomy as Treatment for Nesidioblastosis after Gastric Bypass Surgery


    • Federal University of Santa Maria
    • Department of SurgeryFederal University of Santa Maria
  • Everton N. Faria
    • Federal University of Santa Maria
  • Maristela Beck
    • Federal University of Santa Maria
  • Dener T. Girardon
    • Federal University of Santa Maria
  • Ana Cristina Machado
    • Federal University of Santa Maria
Case Report

DOI: 10.1007/s11695-007-9096-0

Cite this article as:
Alvarez, G.C., Faria, E.N., Beck, M. et al. OBES SURG (2007) 17: 550. doi:10.1007/s11695-007-9096-0

Nesidioblastosis is characterized by hyperfunction of pancreatic islets caused by hypertrophic beta cells. Postprandial symptoms of hypoglycemia are the clinical presentation of the disease. A female patient with diabetes mellitus who underwent a Roux-en-Y gastric bypass began to present postprandial symptoms of hypoglycemia. There was no radiologic (MRI) evidence of insulinoma. Selective arterial calcium-stimulation test identified hyperfunction only in the splenic artery. Laparoscopic spleen-preserving distal pancreatectomy was performed.The patient has been entirely free of any postprandial symptoms for 10 months after the partial pancreatectomy.

Key words

Nesidioblastosisgastric bypass surgeryhypoglycemialaparoscopic distal pancreatectomy
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Copyright information

© Springer Science + Business Media B.V. 2007