Chinese Journal of Integrative Medicine

, Volume 16, Issue 3, pp 216–221

Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension

  • Hao Li李 浩
  • Long-tao Liu刘龙涛
  • Wen-ming Zhao赵文明
  • Jian-gang Liu刘剑刚
  • Ming-jiang Yao姚明江
  • Yong-xiang Han韩永祥
  • Yan-peng Shen沈雁朋
  • Xing-dong Liu刘兴东
  • Li Liu刘 丽
  • Xue-mei Wang王雪梅
  • Lin-lin Cai蔡琳琳
  • Jie Guan官 杰
Original Article

DOI: 10.1007/s11655-010-0216-y

Cite this article as:
Li, H., Liu, L., Zhao, W. et al. Chin. J. Integr. Med. (2010) 16: 216. doi:10.1007/s11655-010-0216-y
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Abstract

Objective

To observe the effect of Chinese medical regimen and integrative medical regimen on quality of life and early renal impairment in elderly patients with isolated systolic hypertension (EISH).

Methods

A multi-center, randomized, double-blinded controlled trail was adopted. A total of 270 cases of EISH were randomly divided into 3 groups: Chinese medicine group (CM), combination group and Western medicine group (WM). The course of treatment was 4 weeks. The clinical blood pressure, integral of quality of life (SF-36 scale), immunoglubin G (IgG), microalbumin (mALB), β2-microglobulin (β2-MG), transferrin (TRF) and N-acetyl-β′-D-glucosa-minidase (NAG) in urine were determined before and after the treatment.

Results

After treatment, systolic blood pressure depressed significantly in each group (P<0.05), and the combination group was superior to CM or WM group in depressing SBP (P<0.05); in each group, integral of quality of life improved in different degree, and combination group was superior to WM group in all 8 dimensions (P<0.05). The level of mALB and β2-MG in urine decreased in all groups (P<0.05), and the combination group was superior to CM group or WM group in decreasing mALB (P<0.05).

Conclusions

Chinese medical regimen has affirmative effect in treating EISH patients, and could lower the systolic blood pressure, improve quality of life and early renal impairment of the patients, and integrative medical regimen has superiority on account of cooperation, and deserves further study.

Keywords

hypertensionelderlyChinese medicineintegrative medicinequality of lifeearly renal impairment

Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Hao Li李 浩
    • 1
  • Long-tao Liu刘龙涛
    • 1
  • Wen-ming Zhao赵文明
    • 1
  • Jian-gang Liu刘剑刚
    • 1
  • Ming-jiang Yao姚明江
    • 1
  • Yong-xiang Han韩永祥
    • 2
  • Yan-peng Shen沈雁朋
    • 2
  • Xing-dong Liu刘兴东
    • 3
  • Li Liu刘 丽
    • 1
  • Xue-mei Wang王雪梅
    • 1
  • Lin-lin Cai蔡琳琳
    • 1
  • Jie Guan官 杰
    • 1
  1. 1.Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijingChina
  2. 2.Traditional Chinese Medicine Hospital of Yanqing CountyBeijingChina
  3. 3.Community Health Service Centers of Yanqing CountyBeijingChina