Chinese Journal of Integrative Medicine

, Volume 15, Issue 2, pp 141–144

Effect of Chinese herbal medicine combined with acitretin capsule in treating psoriasis of blood-heat syndrome type

  • Li-xin Zhang (张立新)
  • Yan-ping Bai (白彦萍)
  • Pei-hua Song (宋佩华)
  • Li-ping You (尤立平)
  • Ding-quan Yang (杨顶权)
Clinical Experience

DOI: 10.1007/s11655-009-0145-5

Cite this article as:
Zhang, L., Bai, Y., Song, P. et al. Chin. J. Integr. Med. (2009) 15: 141. doi:10.1007/s11655-009-0145-5

Abstract

Objective

To observe the clinical curative effect of Chinese herbal medicine combined with acitretin capsule in treating psoriasis of blood-heat syndrome (P-BH).

Methods

Eighty patients of P-BH were randomly assigned to two groups, 39 in Group A and 41 in Group B. Both was treated with Chinese herbal medicines for clearing heat, cooling blood and removing toxic substance, and acitretin capsule was given to Group A additionally, with 8 weeks as one therapeutic course. The clinical curative effect was compared between groups, and the change of psoriasis activity severe index (PASI) scores before and after treatment was observed.

Results

The total effective rate in Group A was 84.2% and that in Group B 68.2%, also showing significance between groups (P<0.01). PASI score lowered significantly after treatment in both groups, showing statistical significance (P<0.01), but no significant difference between groups. Little adverse reaction was found in Group B, while in Group A, the adverse reaction was of even milder degree, which could be alleviated by adjusting the herbal medicine and symptomatic treatment administration.

Conclusions

The effect of Chinese herbal medicine combined with acitretin capsule was superior to Chinese herbal medicine alone in treating P-BH, but the adverse reaction of acitretin capsule could be alleviated by adjusting the herbs used. However, the result is waiting to be verified further by larger samples.

Key Words

psoriasisacitretin capsuleChinese herbal medicine

Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag GmbH 2009

Authors and Affiliations

  • Li-xin Zhang (张立新)
    • 1
  • Yan-ping Bai (白彦萍)
    • 1
  • Pei-hua Song (宋佩华)
    • 1
  • Li-ping You (尤立平)
    • 1
  • Ding-quan Yang (杨顶权)
    • 1
  1. 1.Department of DermatologyChina-Japan Friendship HospitalBeijingChina