In Vitro Cellular & Developmental Biology - Animal

, Volume 46, Issue 3, pp 210–216

The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research

Authors

  • Shirani Sivarajah
    • Singapore Stem Cell Bank, Singapore Stem Cell Consortium, A*STAR
    • Cytentia - Australian Stem Cell Bank
  • Grace Selva Raj
    • Singapore Stem Cell Bank, Singapore Stem Cell Consortium, A*STAR
  • Adam Joshua Varughese Mathews
    • Singapore Stem Cell Bank, Singapore Stem Cell Consortium, A*STAR
  • Norliza Binte Esmail Sahib
    • Singapore Stem Cell Bank, Singapore Stem Cell Consortium, A*STAR
  • Wei Sek Hwang
    • Histopathology, Kandang Kerbau Hospital
    • Singapore Stem Cell Bank, Singapore Stem Cell Consortium, A*STAR
    • Stem Cell Disease Models Laboratory, Institute of Medical Biology, A*STAR
    • Stem Cell Medicine, O’Brien Institute
Article

DOI: 10.1007/s11626-010-9287-1

Cite this article as:
Sivarajah, S., Raj, G.S., Mathews, A.J.V. et al. In Vitro Cell.Dev.Biol.-Animal (2010) 46: 210. doi:10.1007/s11626-010-9287-1

Abstract

The Singapore Stem Cell Bank has generated human embryonic stem cell banks from clinical-grade cell lines ESI-017, ESI-035, ESI-049, and ESI-053. All banks were prepared and characterized according to principles of Good Laboratory Practice for quality assurance. Importantly, each cell line has clearly documented and approved ethical provenance and meets recognized standards for performance and safety. The banks are intended to facilitate the translation of stem cell research to clinical medicine by enabling early phase research and development with high-quality, low-cost cells that are also available as clinical-grade stocks.

Keywords

Human embryonic stem cellsGood laboratory practiceBanksClinical gradeResearch grade

Copyright information

© The Society for In Vitro Biology 2010