The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research
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The Singapore Stem Cell Bank has generated human embryonic stem cell banks from clinical-grade cell lines ESI-017, ESI-035, ESI-049, and ESI-053. All banks were prepared and characterized according to principles of Good Laboratory Practice for quality assurance. Importantly, each cell line has clearly documented and approved ethical provenance and meets recognized standards for performance and safety. The banks are intended to facilitate the translation of stem cell research to clinical medicine by enabling early phase research and development with high-quality, low-cost cells that are also available as clinical-grade stocks.
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- The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research
In Vitro Cellular & Developmental Biology - Animal
Volume 46, Issue 3-4 , pp 210-216
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- Human embryonic stem cells
- Good laboratory practice
- Clinical grade
- Research grade
- Industry Sectors
- Author Affiliations
- 1. Singapore Stem Cell Bank, Singapore Stem Cell Consortium, A*STAR, Singapore, Singapore
- 5. Cytentia - Australian Stem Cell Bank, Melbourne, Australia
- 3. Histopathology, Kandang Kerbau Hospital, Singapore, Singapore
- 2. Stem Cell Disease Models Laboratory, Institute of Medical Biology, A*STAR, Singapore, Singapore
- 4. Stem Cell Medicine, O’Brien Institute, 42 Fitzroy Street, Melbourne, Victoria, 3065, Australia