Journal of General Internal Medicine

, Volume 23, Supplement 1, pp 64-68

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Trial Registration for Public Trust: Making the Case for Medical Devices

  • Ida SimAffiliated withDivision of General Internal Medicine, Department of Medicine, University of California, San FranciscoCenter for Clinical and Translational Informatics, University of California, San Francisco Email author 


Recently, several pharmaceutical companies have been shown to have withheld negative clinical trial results from the public. These incidents have resulted in a concerted global effort to register all trials at inception, so that all subsequent results can be tracked regardless of whether they are positive or negative. These trial registration policies have been driven in large part by concern about the pharmaceutical sector. The medical device industry is much smaller, and different from the pharmaceutical industry in some fundamental ways. This paper examines the issues surrounding registration of device trials and argues that these differences with pharmaceutical should not exempt device trials from registration.


medical device industry trial registration policies public trust