Journal of Gastrointestinal Surgery

, Volume 13, Issue 5, pp 868–873

The Early Use of PET-CT Alters the Management of Patients with Esophageal Cancer

Authors

  • R. N. Williams
    • Department of Surgery, Leicester Royal InfirmaryUniversity Hospital of Leicester NHS Trust
  • S. S. Ubhi
    • Department of Surgery, Leicester Royal InfirmaryUniversity Hospital of Leicester NHS Trust
  • C. D. Sutton
    • Department of Surgery, Leicester Royal InfirmaryUniversity Hospital of Leicester NHS Trust
  • A. L. Thomas
    • Department of Oncology, Leicester Royal InfirmaryUniversity Hospital of Leicester NHS Trust
  • J. J. Entwisle
    • Department of Radiology, Leicester Royal InfirmaryUniversity Hospital of Leicester NHS Trust
    • Department of Surgery, Leicester Royal InfirmaryUniversity Hospital of Leicester NHS Trust
    • Department of Surgery, Leicester Royal InfirmaryInfirmary Square
Original Article

DOI: 10.1007/s11605-009-0812-z

Cite this article as:
Williams, R.N., Ubhi, S.S., Sutton, C.D. et al. J Gastrointest Surg (2009) 13: 868. doi:10.1007/s11605-009-0812-z

Abstract

Introduction

The routine use of positron emission tomography–computed tomography (PET-CT) in the staging of patients with esophageal carcinoma remains contentious, with conflicting reports of its benefit. In our unit, PET-CT has been used routinely in the staging of all patients considered for radical therapy (surgery or chemoradiotherapy). Our aim was to determine the frequency with which PET-CT influenced decision making in the management of patients with carcinoma of the esophagus or gastroesophageal junction.

Methods

CT, PET-CT, and outcome information were collected on 38 patients considered for radical therapy. Patient proformas, with and without PET-CT findings, were constructed and each independently reviewed in a randomized and blinded fashion by five multidisciplinary team members (three surgeons, two oncologists) and a treatment strategy determined.

Results

PET-CT changed the staging for ten patients (26%). This translated into a change in management decision for seven patients (18%). The concordance between individual management plans and treatment intent was 79% for CT (150 of 190 decisions) and it was 92% for PET-CT (175 of 190 decisions). Full concordance between multidisciplinary team members was 66% with CT staging and 74% with the addition of PET-CT.

Conclusion

The use of PET-CT early in the staging algorithm for esophageal carcinoma altered the staging for a quarter of patients and the management for a fifth of patients, supporting its inclusion early in the staging algorithm.

Keywords

PET-CTEsophageal cancerImagingRadionuclide scanning

Copyright information

© The Society for Surgery of the Alimentary Tract 2009