Japanese Journal of Radiology

, Volume 29, Issue 5, pp 301–306

Various computed tomography findings of 2009 H1N1 influenza in 17 patients with relatively mild illness

Original Article

DOI: 10.1007/s11604-010-0558-2

Cite this article as:
Kim, S.Y., Kim, J.S. & Park, C.S. Jpn J Radiol (2011) 29: 301. doi:10.1007/s11604-010-0558-2

Abstract

Purpose

We retrospectively analyzed the computed tomography (CT) findings of H1N1 virus infection in 17 patients with relatively mild illness.

Materials and methods

From September 2009 to January 2010, a total of 17 patients with confirmed H1N1 infection were included in the study (mean age 30.7 years). All patients were managed as outpatients or required short hospitalization without ventilation assistance. The CT scans were assessed for the presence of nodules, ground glass opacity (GGO), consolidation, bronchial wall thickening, reticulation, effusion, and lymph node enlargement. Location and distribution were evaluated.

Results

The most frequent manifestation was a mixture of nodules, consolidation, and GGO (5/17, 29.4%). In one case there was a focal area of bronchiolitis (centrilobular nodules with tree-in-bud appearance), and 10 of 17 cases (58.8%) showed bronchial wall thickening (findings of bronchitis/peribronchitis) and/or other abnormalities. In 16 of the 17 cases (94.1%) there were CT abnormalities with bilateral and random distribution without zonal predominance. Pleural effusions were seen in eight cases (47.1%).

Conclusion

In contrast to several reports so far, CT findings of H1N1 virus infection in patients with mild illness are variable, including suggestive findings of inflammation involving large and/or small airways. This study showed various CT findings overlapping with other viral, atypical, or bacterial pneumonia and even cryptogenic organizing pneumonia.

Key words

Chest CTH1N1 virusSwine-origin influenza AInfectious disease

Copyright information

© Japan Radiological Society 2011

Authors and Affiliations

  • Su Young Kim
    • 1
  • Jeung Sook Kim
    • 2
  • Chan Sup Park
    • 3
  1. 1.Department of RadiologyInje University Ilsan Paik HospitalKyunggi-DoKorea
  2. 2.Department of RadiologyDongguk University Ilsan HospitalGyeonggi-DoKorea
  3. 3.Department of RadiologyKwandong University Myongji HospitalKyunggi-DoKorea