Radiation Medicine

, Volume 25, Issue 6, pp 289–294

Clinical outcome of stereotactic body radiotherapy of 54 Gy in nine fractions for patients with localized lung tumor using a custom-made immobilization system

  • Masahiko Aoki
  • Yoshinao Abe
  • Hidehiro Kondo
  • Yoshiomi Hatayama
  • Hideo Kawaguchi
  • Akira Fujimori
  • Katsumasa Suzaki
  • Morio Seino
  • Takeshi Morita
  • Makoto Souma
  • Takao Tsushima
  • Shingo Takanashi
ORIGINAL ARTICLE

DOI: 10.1007/s11604-007-0141-7

Cite this article as:
Aoki, M., Abe, Y., Kondo, H. et al. Radiat Med (2007) 25: 289. doi:10.1007/s11604-007-0141-7

Abstract

Purpose

The aim of this study was to investigate the clinical outcome of stereotactic body radiotherapy (SBRT) of 54 Gy in nine fractions for patients with localized lung tumor using a custom-made immobilization system.

Methods and materials

The subjects were 19 patients who had localized lung tumor (11 primaries, 8 metastases) between May 2003 and October 2005. Treatment was conducted on 19 lung tumors by fixed multiple noncoplanar conformal beams with a standard linear accelerator. The isocentric dose was 54 Gy in nine fractions. The median overall treatment time was 15 days (range 11–22 days). All patients were immobilized by a thermo-shell and a custom-made headrest during the treatment.

Results

The crude local tumor control rate was 95% during the follow-up of 9.4–39.5 (median 17.7) months. In-field recurrence was noted in only one patient at the last follow-up. The Kaplan-Meier overall survival rate at 2 years was 89.5%. Grade 1 radiation pneumonia and grade 1 radiation fibrosis were observed in 12 of the 19 patients. Treatment-related severe early and late complications were not observed in this series.

Conclusion

The stereotactic body radiotherapy of 54 Gy in nine fractions achieved acceptable tumor control without any severe complications. The results suggest that SBRT can be one of the alternatives for patients with localized lung tumors.

Key words

Stereotactic body radiotherapy Lung cancer Lung metastasis Body frameless Custom-made immobilization system 

Copyright information

© Japan Radiological Society 2007

Authors and Affiliations

  • Masahiko Aoki
    • 1
    • 2
  • Yoshinao Abe
    • 1
    • 2
  • Hidehiro Kondo
    • 1
  • Yoshiomi Hatayama
    • 1
  • Hideo Kawaguchi
    • 1
  • Akira Fujimori
    • 2
  • Katsumasa Suzaki
    • 2
  • Morio Seino
    • 2
  • Takeshi Morita
    • 2
  • Makoto Souma
    • 2
  • Takao Tsushima
    • 3
  • Shingo Takanashi
    • 4
  1. 1.Department of RadiologyHirosaki University School of MedicineAomoriJapan
  2. 2.Division of RadiologyHirosaki University HospitalAomoriJapan
  3. 3.First Department of SurgeryHirosaki University School of MedicineAomoriJapan
  4. 4.Second Department of Internal MedicineHirosaki University School of MedicineAomoriJapan