Cognitive Neurodynamics

, Volume 2, Issue 1, pp 1–5

The physiological and biochemical bases of functional brain imaging


DOI: 10.1007/s11571-007-9033-x

Cite this article as:
Sokoloff, L. Cogn Neurodyn (2008) 2: 1. doi:10.1007/s11571-007-9033-x


Functional brain imaging is based on the display of computer-derived images of changes in physiological and/or biochemical functions altered by activation or depression of local functional activities in the brain. This article reviews the physiological and biochemical mechanisms involved.


Cerebral blood flowCerebral glucose utilizationCerebral metabolismAstrocytesGlycolysisATPasefMRILactate shuttle

Copyright information

© National Institute of Mental Health 2007

Authors and Affiliations

  1. 1.National Institute of Mental Health, National Institutes of HealthBethesdaUSA