Frontiers in Biology

, 6:422

Mitochondrial DNA sequence diversity in three ethnic populations from the South-west Iran: a preliminary study

  • Elham Davoudi-Dehaghani
  • Ali Mohammad Foroughmand
  • Babak Saffari
  • Massoud Houshmand
  • Hamid Galehdari
  • Mehdi Shafa Shariat Panahi
  • Majid Yavarian
  • Mohammad Hossein Sanati
  • Somayeh Torfi
Research Article

DOI: 10.1007/s11515-011-1140-8

Cite this article as:
Davoudi-Dehaghani, E., Foroughmand, A.M., Saffari, B. et al. Front. Biol. (2011) 6: 422. doi:10.1007/s11515-011-1140-8

Abstract

To investigate the genetic structure of human populations in the South-west region of Iran, mitochondrial first hypervariable DNA sequences were obtained from 50 individuals representing three different ethnic groups from Khuzestan Province. Studied groups were Shushtari Persians and Chahar Lang Bakhtiyaries from Indo-European-speaking populations and Bani Torof Arabs from Semitic-speaking linguistic families. Genetic analysis of mtDNA data showed high similarity of Chahar Lang Bakhtiyaries with other Iranian Indo-European-speaking populations while Shushtaries and Bani Torofs had a closer affinity with Semitic-speaking groups rather than to other Iranian populations. The relationship of Chahar Lang Bakhtiyaries and Bani Torof Arabs with their neighbor populations can be explained by linguistic and geographic proximity. Whereas, the greater similarity of Shushtari Persians with West Asian Arabs is probably according to high gene flow between them. This article represents a preliminary study of three major ethnic groups of South-west Iran which investigates the potential genetic substructure of the region.

Keywords

diversitymitochondrial DNAfirst hypervariable sequenceIrangenetic structurepopulation

Supplementary material

11515_2011_1140_MOESM1_ESM.pdf (14 kb)
Supplementary material, approximately 13.7 KB.

Copyright information

© Higher Education Press and Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Elham Davoudi-Dehaghani
    • 1
    • 2
  • Ali Mohammad Foroughmand
    • 1
  • Babak Saffari
    • 3
  • Massoud Houshmand
    • 4
  • Hamid Galehdari
    • 1
  • Mehdi Shafa Shariat Panahi
    • 4
  • Majid Yavarian
    • 5
  • Mohammad Hossein Sanati
    • 4
  • Somayeh Torfi
    • 1
  1. 1.Department of GeneticsShahid Chamran UniversityAhvazIran
  2. 2.Medical Genetics DepartmentTehran University of Medical SciencesTehranIran
  3. 3.Human Genetic Research Group, Iranian Academic Center for Education, Culture & Research (ACECR)Fars Province BranchShirazIran
  4. 4.National Institute for Genetic Engineering and BiotechnologyTehranIran
  5. 5.Hematology Research Center, School of MedicineShiraz University of Medical SciencesShirazIran