Article

Plasmonics

, Volume 6, Issue 3, pp 491-506

A Review on Functionalized Gold Nanoparticles for Biosensing Applications

  • Shuwen ZengAffiliated withSchool of Electrical and Electronic Engineering, Nanyang Technological UniversityCINTRA CNRS/NTU/THALES UMI 3288Singapore Institute of Manufacturing Technology
  • , Ken-Tye YongAffiliated withSchool of Electrical and Electronic Engineering, Nanyang Technological University Email author 
  • , Indrajit RoyAffiliated withDepartment of Chemistry, University of Delhi
  • , Xuan-Quyen DinhAffiliated withCINTRA CNRS/NTU/THALES UMI 3288
  • , Xia YuAffiliated withSingapore Institute of Manufacturing Technology
  • , Feng LuanAffiliated withSchool of Electrical and Electronic Engineering, Nanyang Technological University

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Abstract

Nanoparticle technology plays a key role in providing opportunities and possibilities for the development of new generation of sensing tools. The targeted sensing of selective biomolecules using functionalized gold nanoparticles (Au NPs) has become a major research thrust in the last decade. Au NP-based sensors are expected to change the very foundations of sensing and detecting biomolecules. In this review, we will discuss the use of surface functionalized Au NPs for smart sensor fabrication leading to detection of specific biomolecules and heavy metal ions.

Keywords

Surface plasmon resonance Gold nanoparticles Biosensing Surface functionalization