Article

Plasmonics

, Volume 6, Issue 1, pp 29-34

Enhanced Sensitivity of Surface Plasmon Resonance Phase-Interrogation Biosensor by Using Silver Nanoparticles

  • Tzu-Cheih PengAffiliated withInstitute of Optoelectronic Sciences, National Taiwan Ocean University
  • , Wen-Chi LinAffiliated withInstitute of Optoelectronic Sciences, National Taiwan Ocean University
  • , Chih-Wei ChenAffiliated withInstitute of Optoelectronic Sciences, National Taiwan Ocean University
  • , Din Ping TsaiAffiliated withDepartment of Physics, National Taiwan UniversityInstrument Technology Research Center, National Applied Research Laboratories
  • , Hai-Pang ChiangAffiliated withInstitute of Optoelectronic Sciences, National Taiwan Ocean UniversityInstitute of Physics, Academia SinicaInstrument Technology Research Center, National Applied Research Laboratories Email author 

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Abstract

It is demonstrated that the sensitivity of surface plasmon resonance phase-interrogation biosensor can be enhanced by using silver nanoparticles. Silver nanoparticles were fabricated on silver films by using thermal evaporation. Sizes of silver nanoparticles on silver thin film can be tuned by controlling the deposition parameters of thermal evaporation. By using surface plasmon resonance heterodyne interferometey to measure the phase difference between the p and s polarization of incident light, we have demonstrated that sensitivity of glucose detection down to the order of 10−8 refractive index units can be obtained.

Keywords

Surface plasmons Phase measurement Silver nanoparticles Biosensor