Frontiers of Physics in China

, Volume 4, Issue 4, pp 469–480

Advances in surface plasmon resonance-based high throughput biochips

Authors

  • San-jun Zhang张三军
    • Laboratoire Joliot Curie USR3010, Laboratoire de Physique UMR5672CNRS Ecole Normale Supérieure de Lyon
    • Key Laboratory of Optical and Magnetic Resonance Spectroscopy, and Department of PhysicsEast China Normal University
  • Lotfi Berguiga
    • Laboratoire Joliot Curie USR3010, Laboratoire de Physique UMR5672CNRS Ecole Normale Supérieure de Lyon
  • Juan Elezgaray
    • UMR 5248CNRS-Université Bordeaux 1-ENITAB, IECB
  • Nicolas Hugo
    • Laboratoire Joliot Curie USR3010, Laboratoire de Physique UMR5672CNRS Ecole Normale Supérieure de Lyon
  • Wen-xue Li李文雪
    • Key Laboratory of Optical and Magnetic Resonance Spectroscopy, and Department of PhysicsEast China Normal University
  • Thibault Roland
    • Laboratoire Joliot Curie USR3010, Laboratoire de Physique UMR5672CNRS Ecole Normale Supérieure de Lyon
    • Key Laboratory of Optical and Magnetic Resonance Spectroscopy, and Department of PhysicsEast China Normal University
    • Laboratoire Joliot Curie USR3010, Laboratoire de Physique UMR5672CNRS Ecole Normale Supérieure de Lyon
Review Article

DOI: 10.1007/s11467-009-0069-8

Cite this article as:
Zhang, S., Berguiga, L., Elezgaray, J. et al. Front. Phys. China (2009) 4: 469. doi:10.1007/s11467-009-0069-8

Abstract

This article reviews our recent advances in surface plasmon resonance (SPR) based biochips. It includes four issues, which are the preparation and characterization of high quality gold film, the preparation and characterization of self-assembled monolayer (SAM), dynamics of DNA adsorption on SAMs, and SPR-based microscopies. Numerous topics related to SPR, such as, the modeling of SPR by transmission matrix, effective medium theory, applications of SPR in biology, and SPR-based novel microscopies, are discussed. A novel electrochemical technique, which is extremely useful for the preparation and characterization of high quality SAMs, is also discussed.

Keywords

surface plasmon resonanceeffective medium theoryself-assembled monolayerelectrochemical impedance spectroscopyatomic force microscopySPR-based microscopy

PACS numbers

42.25.Bs42.30.Va68.35.-p68.37.Ps87.80.-y87.85.dh87.85.Rs

Copyright information

© Higher Education Press and Springer Berlin Heidelberg 2009