Chinese Science Bulletin

, Volume 59, Issue 31, pp 4030–4040

Recent advances in brown adipose tissue biology

  • Yanyan Shen
  • Xiaomeng Liu
  • Meng Dong
  • Jun Lin
  • Qianwei Zhao
  • HyuekJong Lee
  • Wanzhu Jin
Review Cell Biology

DOI: 10.1007/s11434-014-0386-3

Cite this article as:
Shen, Y., Liu, X., Dong, M. et al. Chin. Sci. Bull. (2014) 59: 4030. doi:10.1007/s11434-014-0386-3
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Abstract

In mammals, white adipose tissue (WAT) store energy, whereas brown adipose tissue (BAT) burns energy. As a thermogenic organ, BAT can help maintain body temperature during cold exposure. Owing to its important roles in energy metabolism and regulating triacylglycerol levels, BAT has received great attention in treating obesity and its related diseases. Recent studies have suggested that BAT may secrete factor(s)—batokines—to regulate whole-body energy metabolism. In this review, we summarize the recent advances in the formation and function of BAT, as well as molecules that regulate the activity of BAT and beige fat.

Keywords

Brown adipose tissue Batokine Energy regulation Beige adipocyte Anti-obesity 

Copyright information

© Science China Press and Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Yanyan Shen
    • 1
    • 2
  • Xiaomeng Liu
    • 2
    • 3
  • Meng Dong
    • 2
    • 3
  • Jun Lin
    • 2
    • 3
  • Qianwei Zhao
    • 2
    • 3
  • HyuekJong Lee
    • 2
  • Wanzhu Jin
    • 2
  1. 1.University of Science and Technology of ChinaHefeiChina
  2. 2.Key Laboratory of Animal Ecology and Conservation Biology, Institute of ZoologyChinese Academy of SciencesBeijingChina
  3. 3.The University of the Chinese Academy of SciencesBeijingChina

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