Science China Life Sciences

, Volume 54, Issue 8, pp 786–792

Building the DREAM interactome

  • Marcos Rivas
  • Diego Villar
  • Paz González
  • Xosé M. Dopazo
  • Britt Mellstrom
  • José R. Naranjo
Open Access
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DOI: 10.1007/s11427-011-4196-4

Cite this article as:
Rivas, M., Villar, D., González, P. et al. Sci. China Life Sci. (2011) 54: 786. doi:10.1007/s11427-011-4196-4

Abstract

DREAM/calsenilin/KChIP3 is a calcium binding protein of the neuronal calcium sensor superfamily. DREAM interacts with DRE (downstream regulatory element) sites in the DNA to regulate transcription and with many proteins to exert specialized functions in different subcellular compartments. Work from different laboratories has identified a growing list of interacting proteins that constitutes the DREAM interactome. The knowledge of these interactions has greatly contributed to the understanding of the various physiological functions of DREAM.

Keywords

calsenilin KChIP3 protein-protein interaction 
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© The Author(s) 2011

Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  • Marcos Rivas
    • 1
    • 2
  • Diego Villar
    • 1
    • 2
  • Paz González
    • 1
    • 2
  • Xosé M. Dopazo
    • 1
    • 2
  • Britt Mellstrom
    • 1
    • 2
  • José R. Naranjo
    • 1
    • 2
  1. 1.Department of Molecular and Cellular Biology, National Center of BiotechnologyConsejo Superior Investigaciones CientificasMadridSpain
  2. 2.Centro Investigacion Biomedica En Red de Enfermedades Neurodegenerativas-Centro Nacional de BiotecnologiaMadridSpain

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