Science China Chemistry

, Volume 59, Issue 2, pp 171–174

C–H allylation of N-aryl-tetrahydroisoquinolines by merging photoredox catalysis with iodide catalysis

Articles SPECIAL TOPIC · Organic Photochemistry

DOI: 10.1007/s11426-015-5548-x

Cite this article as:
Feng, Z., Zeng, T., Xuan, J. et al. Sci. China Chem. (2016) 59: 171. doi:10.1007/s11426-015-5548-x

Abstract

A dual catalytic system, combing visible light photoredox catalysis and iodide catalysis, has been developed for the functionalization of inert C–H bonds. By doing so, radical allylation reactions of N-aryl-tetrahydroisoquinolines (THIQs) were realized under extremely mild conditions, affording a wide variety of allyl-substituted THIQs in up to 78% yields.

Keywords

visible light photocatalysis iodide catalysis allylation tetrahydroisoquinolines 

Supplementary material

11426_2015_5548_MOESM1_ESM.pdf (1.8 mb)
Supplementary material, approximately 1037 KB.

Copyright information

© Science China Press and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.CCNU-uOttawa Joint Research Center, College of ChemistryCentral China Normal UniversityWuhanChina