Science China Chemistry

, Volume 56, Issue 6, pp 685–701

Decarbonylative C-C bond forming reactions mediated by transition metals

Review

DOI: 10.1007/s11426-012-4791-7

Cite this article as:
Dermenci, A. & Dong, G. Sci. China Chem. (2013) 56: 685. doi:10.1007/s11426-012-4791-7

Abstract

New methods for carbon-carbon (C-C) forming reactions are constantly emerging in the field of organic synthesis. In this review, a brief history followed by recent developments of decarbonylative C-C forming reactions mediated by transition metals is described. Many different substrates are presented and the review is organized by the different carbonyl precursors, such as acyl chlorides, aldehydes, anhydrides, esters and ketones, used in the respective transformations. Furthermore, the broad scope of these reactions is exhibited by the application to several reaction types (e.g. Heck-type reactions, Suzuki cross-coupling type reactions, C-H activation, etc.) as well as a natural product synthesis (e.g. muscroride A). While several examples are provided, this review marks the beginning of a new field that is still in its infancy and for what might be a new approach to achieve highly efficient reactions that come closer to meeting the standards of chemical economies (e.g. atom, redox, step, etc.) and green chemistry.

Keywords

transition metal decarbonylation C-C formation green chemistry 

Copyright information

© Science China Press and Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Chemistry and Biochemistrythe University of Texas at AustinAustinUSA

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