Science China Chemistry

, Volume 53, Issue 3, pp 562–568

Pictet-Spengler condensation reactions catalyzed by a recyclable H+-montmorillonite as a heterogeneous Brønsted acid

  • YuFeng Wang
  • ZhanBo Song
  • ChunXia Chen
  • JinSong Peng
Articles

DOI: 10.1007/s11426-010-0073-4

Cite this article as:
Wang, Y., Song, Z., Chen, C. et al. Sci. China Chem. (2010) 53: 562. doi:10.1007/s11426-010-0073-4

Abstract

Catalytic performance of different cation-exchanged montmorillonite clays has been investigated in the Pictet-Spengler C-C bond forming reaction. H+-Montmorillonite was found to be a very efficient and reusable catalyst for the endo cyclization of β-phenylethylamine derivatives with aldehydes under solvent-free conditions. In addition, an aqueous condensation version for the synthesis of tetrahydro-β-carbolines using the H+-montmorillonite catalyst has been developed. In these environmentally friendly processes, the use of organic solvents was avoided and the catalyst was recycled with maintenance of high catalytic activity.

Keywords

heterogeneous catalysiscatalyst recyclingmesoporous materialsgreen synthesis

Copyright information

© Science China Press and Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • YuFeng Wang
    • 1
  • ZhanBo Song
    • 1
  • ChunXia Chen
    • 1
  • JinSong Peng
    • 1
  1. 1.Department of Chemistry and Chemical Engineering, College of ScienceNortheast Forestry UniversityHarbinChina