Journal of Natural Medicines

, Volume 63, Issue 1, pp 102–104

Sesquiterpenes from Curcuma comosa


  • Yang Qu
    • School of Traditional Chinese Materia MedicaShenyang Pharmaceutical University
  • Fengming Xu
    • Kyoto Pharmaceutical University
  • Seikou Nakamura
    • Kyoto Pharmaceutical University
  • Hisashi Matsuda
    • Kyoto Pharmaceutical University
  • Yutana Pongpiriyadacha
    • Rajamangala University of Technology Srivijaya
  • Lijun Wu
    • School of Traditional Chinese Materia MedicaShenyang Pharmaceutical University
    • Kyoto Pharmaceutical University
Natural Medicine Note

DOI: 10.1007/s11418-008-0282-8

Cite this article as:
Qu, Y., Xu, F., Nakamura, S. et al. J Nat Med (2009) 63: 102. doi:10.1007/s11418-008-0282-8


From the dried rhizomes of Curcumacomosa cultivating in Thailand, 26 known sesquiterpenes were isolated: zederone, zederone epoxide, furanodienone, isofuranodienone, 1(10)Z,4Z-furanodiene-6-one, glechomanolide, dehydrocurdione, neocurdione, curdione, 7α-hydroxyneocurdione, 7β-hydroxycurdione, germacrone-1(10),4-diepoxide, germacrone, 13-hydroxygermacrone, curzerenone, curcolonol, alismol, alismoxide, zedoarondiol, isozedoarondiol, procurcumenol, isoprocurcumenol, aerugidiol, zedoalactone B, curcumenone, and curcumadione. Their structures were elucidated on the basis of physicochemical evidence. Among them, glechomanolide, curzerenone, curcolonol, alismol, alismoxide, and zedoarondiol showed no significant optical activities, so they may be artifact products during the isolation or drying process.


Curcuma comosaZingiberaceaeSesquiterpenes

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© The Japanese Society of Pharmacognosy and Springer 2008