, Volume 61, Issue 4, pp 367-370
Date: 14 Jul 2007

Biologically active gangliosides from echinoderms

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Abstract

This review will summarize the authors’ studies on the structure and the biological activities of the gangliosides from echinoderms. Over 40 gangliosides have been obtained and characterized from 13 kinds of echinoderms, namely, Acanthaster planci, Asterina pectinifera, Asterias amurensis versicolor, Astropecten latespinosus, Luidia maculata, Linckia laevigata (starfish), Cucumaria echinata, Holothuria pervicax, H. leucospilota, Stichopus japonicus, S. chloronotus (sea cucumber), Comanthus japonica (feather star) and Ophiocoma scolopendrina (brittle star). The structural feature of the echinoderms gangliosides was their unique carbohydrate moieties. The biological property of the gangliosides from echinoderms, taking up in this review, was mainly neuritogenic activity.