AGE

, Volume 36, Issue 1, pp 417–426

Prevalence of site-specific thigh sarcopenia in Japanese men and women

  • Takashi Abe
  • Robert S. Thiebaud
  • Jeremy P. Loenneke
  • Mark Loftin
  • Tetsuo Fukunaga
Article

DOI: 10.1007/s11357-013-9539-6

Cite this article as:
Abe, T., Thiebaud, R.S., Loenneke, J.P. et al. AGE (2014) 36: 417. doi:10.1007/s11357-013-9539-6

Abstract

The purpose of this study was to compare the prevalence of severe sarcopenia detected by total skeletal muscle mass (SM) index and of site-specific thigh sarcopenia for differing age groups in men and women. Japanese nonobese men and women aged 20 to 85 (n = 1,994, 55 % women) had muscle thickness (MTH) measured by ultrasound at six sites on the anterior and posterior aspects of the body. SM was estimated from ultrasound-derived prediction equations. Site-specific thigh sarcopenia was calculated using ultrasound-measured MTH at the anterior and posterior aspects of the thigh (MTH ratio, anterior 50 %/posterior 50 % thigh MTH (A50/P50 MTH)). Sarcopenia was defined as a SM index (SM divided by height2) of >2 standard deviations (SD) below the mean for young adults. Site-specific thigh sarcopenia was defined as a ratio of A50/P50 MTH of >2 SD below the mean for young adults. Age was inversely correlated to SM index and A50/P50 MTH in men (r = −0.480 and r = −0.522) and women (r = −0.243 and r = −0.516). The prevalence rate of sarcopenia was less than 3 % for women under the age of 60, 7 % for ages 60–69, and 24 % for ages 70–80. In men, the prevalence rate of sarcopenia was less than 7 % under the age of 50, 18 % for ages 50–59, 33 % for ages 60–69, and 47 % for ages 70–85. Compared to the sarcopenia estimated by SM index, there was a higher prevalence of site-specific thigh sarcopenia observed in both sexes. These results suggest that site-specific thigh sarcopenia appears before it is able to be detected at the whole body level.

Keywords

AgingSkeletal muscle massUltrasoundThigh muscle thickness

Copyright information

© American Aging Association 2013

Authors and Affiliations

  • Takashi Abe
    • 1
  • Robert S. Thiebaud
    • 2
  • Jeremy P. Loenneke
    • 2
  • Mark Loftin
    • 1
  • Tetsuo Fukunaga
    • 3
  1. 1.Department of Health, Exercise Science & Recreation ManagementUniversity of MississippiOxfordUSA
  2. 2.Department of Health and Exercise ScienceUniversity of OklahomaNormanUSA
  3. 3.National Institute of Fitness and Sports in KanoyaKanoyaJapan